Genicular artery embolization (GAE) is a minimally invasive, FDA-approved treatment for knee osteoarthritis (OA). It requires no surgery, no hospitalization and no lengthy recovery. It is highly effective at relieving pain, and if you seek GAE treatment for OA early enough, you may not ever need surgery for your condition.
GAE works by targeting the abnormal blood vessels within the synovium (Joint lining) that are responsible for inflammation and cartilage loss. By embolizing or “blocking” these abnormal vessels, blood flow is reduced to normal levels. Pain is significantly reduced, and cartilage loss is halted or significantly slowed.
Take our quiz to see if you qualify for GAE treatment »
During the procedure, one of our interventional radiologists uses imaging to guide a catheter through the vascular system and to the genicular artery feeding the joint lining. Tiny particles are injected that block the flow of blood through the abnormal blood vessels within the joint lining, which in turn decreases the inflammatory mediators that the joint lining secretes. The result is fast and long-term pain relief, as well as improved function and quality of life. Additionally, it does not preclude the ability to have knee replacement surgery in the future.
A clinical study performed in 2021 demonstrated that the average pain scores decreased from 8 out of 10 to 3 out of 10 within the first week of the procedure.1
I just had my right knee done June 10, 2025. Both my knees are now done and I had the GAE procedure. I really like the doctors and staff here they truly care about what your going through. I was able to stand and do my dishes for the first time in months. When we pray our prayers eventually get answered. Thank you so much to everyone at the clinic.
North Star is the best in Minnesota! The staff is so friendly and treat you like family. And Dr. Golzarian is great! I thought I would have to live with knee pain for the remainder of my life. But Dr. Golzarian has made sure I don’t! Not everyday is totally pain free. But I can walk freely, I can get up off the couch without hesitation. I no longer have to rub my knee before making any sudden movements. Thank you North Star!!!
After GAE on my left knee I now can go and walk around the store with my family, I haven’t done that in years. Something as simple as stepping over a curb is possible now and without pain. I can’t wait to have my second knee done!
I definitely am glad that I gave them my trust to provide me with the amazing experience that I had when I came in to have my procedure done I was very concerned because I have extreme vertigo that has been disregarded by previous medical professionals. That did not happen whatsoever when I came in for my procedure with North Star Vascular! When I was speaking with my prep team over the phone, she made sure that she was able to provide the best care for me. And they did. Throughout the prepping and the procedure they were attentive, accommodating, and the most caring team I have ever dealt with. I can’t wait for my follow-up visit so we can schedule my other knee procedure. I went from a resting level pain of eight in my right knee, which is the worst or actually was the worst to a resting pain of zero I can climb stairs, I can walk , literally pain-free and that was the second day after surgery. I feel strongly that you can put your trust into North Star Vascular and Dr. Golzarian and his team! I can’t stress enough the amazement and delight to be pain free! Take a chance—-you won’t regret it!
My mom has so much relief after having her procedure and is scheduled for the left knee. Great service!
Yesterday, Dr. Golzarian operated on my right knee, which had severe arthritis. Now that 24 hours have passed, I feel like I’m in my twenties when I’m exactly 80 years old. I just don’t know and can’t express my gratitude to you and your dear colleagues. I think you performed a miracle. All the orthopedists I went to for my knee bone wear unanimously said that they should replace with an artificial knee. But now I am walking without any pain and my blood pressure is rising. I just wanted to say that I thank you and your colleagues at North Star from the bottom of my heart.
Having a fantastic climbing trip in the Dolomites. My knee feels so much better than before the procedure. I hiked into a mountain hut carrying 40 lbs of climbing gear yesterday, and was able to enjoy the climbs today! I have not taken any pain relievers on the trip (yet). None since the procedure!
The GAE procedure helped a lot. I have less knee pain and can enjoy being myself again. I had a great experience [with North Star], and I look forward to getting my right knee done!
Excellent experience, knowledgeable and caring staff! Feels like they turned back the clock 5+ years on my knee!
Dr. Golzarian, thank you for the very good procedure you did to treat my knee osteoarthritis, when all the other doctors wanted to give me an artificial knee because of the advanced osteoarthritis. You gave me the hope of walking again without pain after two hours of performing GAE on my knee. I am 80 years old. I am old, for the first time in six years, I was able to walk again without pain after the procedure, I was able to go up and down the stairs. For this reason, while thanking and appreciating you and your skilled colleagues, I want you to know that I am always grateful to you. Thank you.
For more information or to schedule a consultation, contact us at North Star Vascular and Interventional. We’re here to provide friendly, expert care and help you stay healthy and active.
NSVI’s providers offer extensive experience with the diagnosis and minimally invasive treatment of knee osteoarthritis. Our expertise in x-ray-guided procedures will optimize your outcome without the risks of surgery. In addition, we offer a comfortable outpatient center—a more patient-friendly alternative to a busy hospital or medical center. It’s a safe and convenient environment with special emphasis placed on patient service.
Our doctors are fellowship trained in vascular and interventional radiology. With more than 13 years of education and training, they are among the most highly trained doctors practicing medicine today and are uniquely qualified to provide both diagnostic evaluations as well as the required treatment.
If you believe you are a candidate for a minimally invasive knee osteoarthritis treatment, we invite you to schedule a consultation with us. We are happy to work with your doctor(s) and other members of your care team to find the right treatment for your specific condition.
Genicular Artery Embolization (GAE) is a minimally invasive procedure that reduces chronic knee pain from osteoarthritis by blocking specific arteries to decrease inflammation and pain. At our clinic, our experts specialize in this effective treatment, using the latest techniques to ensure optimal results.
GAE blocks abnormal blood vessels in the knee that cause chronic inflammation. Using a tiny catheter, we inject small particles to reduce blood flow to these areas, easing pain and swelling without any incisions. Trust our experts to deliver this advanced procedure with precision and care.
GAE is highly effective, with over 80% of patients experiencing substantial pain reduction and improved quality of life. Our dedicated team is here to help you achieve these results with a patient-centered approach.
The results can vary from a few weeks to several years. Most patients see significant pain relief for two years or more. Our personalized care aims to maximize the duration of your relief, helping you return to your active lifestyle quickly.
Yes, many insurance plans cover GAE. We will help verify your coverage and explore payment options to make the process as smooth and stress-free as possible.
Blood flow to the knee is not entirely cut. GAE safely targets only the abnormal vessels causing inflammation, restoring a normal blood flow and reducing pain. Our skilled specialists ensure the procedure is performed safely and effectively, prioritizing your well-being.
GAE is very safe with a low risk of complications. Our providers will discuss any potential risks with you before the procedure, ensuring you are well-informed and comfortable. Our team’s extensive experience and commitment to safety make us a trusted choice for your care.
Side effects are usually mild, such as temporary pain, bruising, and swelling at the catheter site. Serious side effects are rare, but we will monitor your recovery closely, providing support and guidance every step of the way.
Yes, if knee pain returns, GAE can be repeated. Our experts will evaluate your condition to determine if a repeat procedure is appropriate. We’re here to help you find lasting relief.
GAE is ideal for patients with chronic knee pain from osteoarthritis who haven’t responded to other treatments. We will assess your condition to confirm if GAE is right for you, using our expertise to provide personalized solutions for pain relief.
GAE may not be suitable for those with severe peripheral artery disease, certain infections, or allergies to embolization materials. Our providers will review your case to ensure you receive the most appropriate care, tailoring our approach to meet your specific needs.
At our clinic, we treat our patients like family. Our world-class physicians have pioneered treatments like GAE, ensuring you receive top-notch, personalized care. Our friendly staff is dedicated to making your experience exceptional, so you leave not just satisfied, but thrilled with your care. Contact us today to schedule a consultation and take the first step towards a pain-free life!
